Neuroscience

From infancy through older adulthood, neuroscience discoveries at the University of Virginia are improving lives and expanding our understanding of the brain. The UVA Brain Institute serves as a hub for interdisciplinary collaboration and groundbreaking research, driving new discoveries and accelerating progress against complex neurological conditions such as Alzheimer’s disease and autism.
MRI or magnetic resonance imaging of the head and brain. Close up
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Medicine

Decades of UVA Research Yields New Parkinson’s Drug

The FDA has approved Juvmo (tavapadon), a once-daily pill for Parkinson’s disease rooted in decades of UVA Health research by Richard Mailman and Xuemei Huang. Unlike levodopa, this first-in-class D1 agonist selectively activates dopamine receptors, potentially offering fewer side effects and longer-lasting symptom relief for the 11 million people worldwide living with Parkinson’s.

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Medicine

Focused Ultrasound to Transform Brain Disease Treatment

UVA Health researchers report focused ultrasound is nearing a breakthrough for treating brain tumors, Alzheimers and Parkinsons by delivering gene therapies across the blood-brain barrier. New non-viral nanoparticle approaches, led by Richard Price and colleagues, could enable precise, repeatable treatments targeting tumor cells while engaging the immune system, with findings published across three scientific papers.

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Immunology

Experimental MS Drug Reverses Paralysis, Vision Loss in Lab Model

A UVA Health scientist has developed a drug, Kamuvudine K-9, that reversed paralysis and vision loss in a mouse model of multiple sclerosis, going beyond existing treatments that only prevent future attacks. Derived from HIV drugs, K-9 preserved nerve fibers and reduced nerve damage markers, offering promising evidence for future human clinical trials.

Evans collaborates with team members in MRI
Neuroscience

How the Brain Learns

Video

Through neuroscience and cross-disciplinary collaboration, Tanya Evans examines the memory systems that influence learning, with the goal of improving outcomes for children who struggle in school.

Evans collaborates with team members in MRI
Annual Report

Understanding the Learning Brain One Collaboration at a Time

UVA neuroscientist Tanya Evans investigates why some children struggle with reading or math by studying the brain mechanisms behind learning differences like dyslexia. Through cross-disciplinary collaborations and a $3 million NIH grant, her research explores how declarative and procedural memory systems shape skill development, with findings pointing toward targeted interventions for students who need them most.

Sarah Flowers image
Medicine

Sarah Flowers speaks at U Ask, UVA Answers

Video

U Ask, UVA Answers returns this fall with talks at Jefferson-Madison Regional Library and new sessions at Crozet Library. Sarah Flowers kicks off September discussing Alzheimer’s disease and genetics research. Upcoming speakers include Bryan Berger on food biotechnology in October and Natasha Diba Sheybani on ultrasound breast cancer treatment in November.